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KMID : 0387820130200010075
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Clinical Pediatric Hematology-Oncology
2013 Volume.20 No. 1 p.75 ~ p.78
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Growing Teratoma Syndrome of the Pineal Gland Recognized Very Early during Chemotherapy in a Child with a Non-Germinomatous Germ-Cell Tumor
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Zhang Zhaoxia
Yoon Byung-Gyu
Baek Hee-Jo
Park Sun-Ju
Han Dong-Kyun
Park Soo-Min
Jung Tae-Young
Lee Min-Cheol
Kook Hoon
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Abstract
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The growing teratoma syndrome (GTS) is defined as the development of mature low-grade elements in the absence of a recurrent non-germinomatous germ-cell tumor (NGGCT) after partial response to multimodal treatment. It is uncommon and may occur in intracranial NGGCTs. Here, we report that a 7-year-old boy with intracranial NGGCT presented with precocious puberty and developed growing teratoma syndrome only 2 weeks after the first cycle of chemotherapy.
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KEYWORD
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Growing teratoma syndrome, Non-germinomatous germ cell tumors, Immature teratoma
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